Basic Information
VIS ID
TVIS44018000
Fusion event
HTLV-1-ASIC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
32260569/33933550 (Hg38)
End
32260569/33933550 (Hg38)
Orient
-
Location type
Intronic
Target gene
ASIC2
Nearest miRNA
hsa-mir-1180/Upstream/1583348; hsa-mir-10226/Downstream/3100195;
Nearest TSS
ENST00000595228/Upstream/865; ENST00000582685/Downstream/42981;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/640103, chr17-CpG: 46/Downstream/106374
Upstream sequence
GCAAGGCCAATGAGATTCAGCCATTTTTCAAATGAATAAGCTCAGGCTTGGAAAGAGGTGAGTACGGGACAGAGCAGGAATTGATTTCAGCGACTGCACC
Downstream sequence
GAGCTGTGAGGGACAGTGGCTGGGTGACCTGGGAAGTCACCTCTTCTAGGACCTCATGCACTGGGAATGTGCCCTAATCCAGGGGATGAGGACCAACTTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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