VISDB Viral Integration Site DataBase

VIS ID

TVIS44018011

Fusion event

HTLV-1-ANKFY1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

p13.2

Reference genome

Start

End

4152521/4249226 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-130b-3p ; hsa-mir-128-3p ; hsa-mir-1-3p ; hsa-mir-103a-3p ; hsa-mir-101-3p ; hsa-mir-93-5p ; hsa-mir-760 ; hsa-mir-106b-5p ; hsa-mir-4793-3p ; hsa-mir-7703 ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-4713-5p ; hsa-mir-218-5p ; hsa-mir-20a-5p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6729-5p ; hsa-mir-4649-5p ; hsa-mir-1273a ; hsa-mir-661 ; hsa-mir-4486 ; hsa-mir-2116-3p ; hsa-mir-532-3p ; hsa-mir-150-5p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-186-3p ; hsa-mir-6849-3p ; hsa-mir-508-5p ; hsa-mir-576-5p ; hsa-mir-633 ; hsa-mir-4286 ; hsa-mir-877-3p ; hsa-mir-6513-5p ; hsa-mir-1224-3p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-6788-5p ; hsa-mir-1273h-5p ; hsa-mir-30c-2-3p ; hsa-mir-7977 ; hsa-mir-30c-1-3p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-6090 ; hsa-mir-4300 ; hsa-mir-6827-5p ; hsa-mir-4761-5p ; hsa-mir-7855-5p ; hsa-mir-4710 ; hsa-mir-4792 ; hsa-mir-9-5p ; hsa-mir-6832-3p ; hsa-mir-6814-5p ; hsa-mir-3691-3p ; hsa-mir-2114-5p ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-3162-5p ; hsa-mir-3649 ; hsa-mir-7112-3p ; hsa-mir-107 ; hsa-mir-383-3p ; hsa-mir-34c-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6760-5p ; hsa-mir-193b-3p ; hsa-mir-519d-3p ; hsa-mir-193a-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-1197 ; hsa-mir-1224-5p ; hsa-mir-1293 ; hsa-mir-323a-5p ; hsa-mir-4483 ; hsa-mir-4651 ; hsa-mir-4751 ; hsa-mir-5004-5p ; hsa-mir-608 ; hsa-mir-6801-5p

Nearest miRNA

hsa-mir-1253/Upstream/1501044; hsa-mir-10226/Downstream/720476;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/105153, chr17-CpG: 74/Downstream/14184

Upstream sequence

CAAGAATGATTTTTAGAACACTCTTCCTTCTAGGTcaggagttggcatactttccgtacagggccacatagcaaatattttaggctttgggagccataca

Downstream sequence

gtctctggggcactactcaactctgccagttggaacacaaaagtacaaattaatgaatgtggctgtttccctaaaaatactttatttatgaacactgaaa