Basic Information
VIS ID
TVIS44018020
Fusion event
HTLV-1-LINC02089 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
50960862/52883502 (Hg38)
End
50960862/52883502 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02089
Nearest miRNA
hsa-mir-10226/Upstream/2114772; hsa-mir-1250/Downstream/4007768;
Nearest TSS
ENST00000595228/Upstream/21381; ENST00000623702/Downstream/102018;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/724628, chr17-CpG: 17/Downstream/873787
Nearby gene
C17orf112(No orient, 102018)
Upstream sequence
gttcatggtctcgctggcttcaggagtgaagctgcagaccttccccagtgagtgttaacagttcatacaggcagtgtggacccaaagagtgagcagcagc
Downstream sequence
aagagtcattgcaacgagcaaaagaacaaagcttccacagtgtggaaggggaccccagcgggttgccactgctggctggggcagcctgcttttattctct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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