Basic Information
VIS ID
TVIS44018026
Fusion event
HTLV-1-NUP88 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
5322731/5419411 (Hg38)
End
5322731/5419411 (Hg38)
Orient
+
Location type
Exonic
Target gene
NUP88
Nearest miRNA
hsa-mir-1253/Upstream/449261; hsa-mir-10226/Downstream/1236029;
Nearest TSS
ENST00000595228/Upstream/1182; ENST00000575711/Downstream/55;
Nearest CpG islands
chr17-CpG: 95/Target, None/Upstream, None/Downstream
Upstream sequence
CGATCCCGGTGAGGGTCACTTCCAAGATCGGCCTGGCATTACCTGGTACTGGGACAGGGCGGGCTCTTCGCCGCCGCCGCTGGGGCCCCGAAGGCGAACG
Downstream sequence
ACTAAGAAGGAGCTGTCTTCTCCGTCCCACAGGAAAAGCTCTCCGCCGAGGCCAAAGACCACGTTTCTCGTCAGCAACTGCGGCGGCGGCGACGAAGGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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