Basic Information
VIS ID
TVIS44018030
Fusion event
HTLV-1-ANKFN1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
54261295/56183934 (Hg38)
End
54261295/56183934 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANKFN1
Nearest miRNA
hsa-mir-10226/Upstream/5415204; hsa-mir-1250/Downstream/707336;
Nearest TSS
ENST00000595228/Upstream/9759; ENST00000573365/Downstream/43983;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/338156, chr17-CpG: 40/Downstream/326659
Upstream sequence
caacacttcagcggatgaagaaactgcatatgtggtaccaatattaagcaaactaaaattagaagtaaagccttcagatgtgactgaattactgtcatct
Downstream sequence
catgatacatcttgaatggatattgagttgcttcatatgaataagcaaagaaagtggtttcttgccatgggatccactctttggtgaatatgctgtgaac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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