Basic Information
VIS ID
TVIS44018034
Fusion event
HTLV-1-LOC339166 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
5803586/5900266 (Hg38)
End
5803586/5900266 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LOC339166
Nearest miRNA
hsa-mir-1253/Upstream/930116; hsa-mir-10226/Downstream/755174;
Nearest TSS
ENST00000595228/Upstream/127340; ENST00000572764/Downstream/157541;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/398984, chr17-CpG: 112/Downstream/169729
Upstream sequence
TTTCAGAGTGGCTTGCTGGTAAGGGTTGGGTGGAGGCTGGAGGGGATAGAGGGAGATTGCAAATGGTGACCAAGTCAGAAGAGAAGCACATCCACAATGG
Downstream sequence
AGTGTCCATGAAGGTGGCCTGAAGTGTCCTCTGTGTCCAGGGGATCTCTAGTGACATTGGTGGGTGGGTGGGGGTTCTTCGTCTAGAAGGATGGGACAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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