Basic Information
VIS ID
TVIS44018046
Fusion event
HTLV-1-chr17 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
6935390/7032071 (Hg38)
End
6935390/7032071 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1253/Upstream/14049; hsa-mir-10226/Downstream/191226;
Nearest TSS
ENST00000595228/Upstream/5280; ENST00000575844/Downstream/4004;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/7863, chr17-CpG: 78/Downstream/3747
Nearby gene
BCL6B(+2429) ;
Nearest cancer related gene
BCL6B(TSG, +2429) ;
Upstream sequence
ctgcagtggctctgcccctgtgacaagtccctgcctgggcccctaggctttcaacaacatcctttgaaatccatgtggagactgccaagccttcacagct
Downstream sequence
cttactttctgcaagactgcagaattagcaccacaaggatgcagcaaaggtctatgatttgcaccttctggagcttcaatacaagcaacacacacacaca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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