Basic Information
VIS ID
TVIS44018049
Fusion event
HTLV-1-LINC00673 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
70521584/72525444 (Hg38)
End
70521584/72525444 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC00673
Nearest miRNA
hsa-mir-10226/Upstream/3425788; hsa-mir-1250/Downstream/2223169;
Nearest TSS
ENST00000595228/Upstream/55078; ENST00000584975/Downstream/66896;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/401143, chr17-CpG: 36/Downstream/14899
Upstream sequence
CAGGGGTCCCCAGCGGGCCTCCCCAGCATCCTGGGACTCTACTTCCTCCAGGGGAAGGTAAATAAAATCAGCTGATCAACCAATCAGCTCACTGGAAAGC
Downstream sequence
AGGAAACAGAAGGACTCTCTAAAATCAGCCCAGATTGCTACACAGGAATTGTCCAAAGTCCAAAAAGTTGCCACTCTTTAAAGGAGGCAGAGGAGAATAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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