VISDB Viral Integration Site DataBase

VIS ID

TVIS44018052

Fusion event

HTLV-1-SSTR2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

q25.1

Reference genome

Start

End

71165843/73169704 (Hg38)

Orient

+

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-378a-5p ; hsa-mir-6778-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3653-5p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1227-3p ; hsa-mir-4252 ; hsa-mir-191-3p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-106a-3p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-564 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-4695-3p ; hsa-mir-6787-3p ; hsa-mir-6736-3p ; hsa-mir-183-5p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-5197-5p ; hsa-mir-1262 ; hsa-mir-4701-3p ; hsa-mir-661 ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p ; hsa-mir-6807-5p ; hsa-mir-192-5p ; hsa-mir-203b-3p ; hsa-mir-215-5p ; hsa-mir-3187-3p ; hsa-mir-3663-5p ; hsa-mir-4435 ; hsa-mir-4635 ; hsa-mir-4680-5p ; hsa-mir-4716-5p ; hsa-mir-4755-3p ; hsa-mir-4781-3p ; hsa-mir-548s ; hsa-mir-588 ; hsa-mir-6131 ; hsa-mir-7158-3p

Nearest miRNA

hsa-mir-10226/Upstream/4070048; hsa-mir-1250/Downstream/1578909;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/3493, chr17-CpG: 132/Downstream/22564

Upstream sequence

CTGCCTTTCTTGGCTATGCAGGTGGCTCTGGTCCACTGGCCCTTTGGCAAGGCCATTTGCCGGGTGGTCATGACTGTGGATGGCATCAATCAGTTCACCA

Downstream sequence

GCATCTTCTGCCTGACAGTCATGAGCATCGACCGATACCTGGCTGTGGTCCACCCCATCAAGTCGGCCAAGTGGAGGAGACCCCGGACGGCCAAGATGAT