VISDB Viral Integration Site DataBase

VIS ID

TVIS44018060

Fusion event

HTLV-1-RNF157 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr17

Cytoband

q25.1

Reference genome

Start

End

74233358/76237277 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-18a-5p ; hsa-mir-6880-5p ; hsa-mir-6870-5p ; hsa-mir-7111-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-6825-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-766-5p ; hsa-mir-6077 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-605-3p ; hsa-mir-6798-5p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-6893-5p ; hsa-mir-940 ; hsa-mir-6808-5p ; hsa-mir-3714 ; hsa-mir-2355-3p ; hsa-mir-3674 ; hsa-mir-676-3p ; hsa-mir-6772-3p ; hsa-mir-580-3p ; hsa-mir-7975 ; hsa-mir-4473 ; hsa-mir-636 ; hsa-mir-4732-5p ; hsa-mir-6832-5p ; hsa-mir-3907 ; hsa-mir-4448 ; hsa-mir-4268 ; hsa-mir-539-5p ; hsa-mir-6730-5p ; hsa-mir-6080 ; hsa-mir-520f-3p ; hsa-mir-302c-3p ; hsa-mir-512-3p ; hsa-mir-5584-5p ; hsa-mir-6873-5p ; hsa-mir-4735-3p ; hsa-mir-18b-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-3191-5p ; hsa-mir-1248 ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-1200 ; hsa-mir-6778-3p ; hsa-mir-4682 ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-33b-5p ; hsa-mir-33a-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4634 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6868-3p ; hsa-mir-1237-3p ; hsa-mir-150-5p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6814-5p ; hsa-mir-4650-5p ; hsa-mir-1972 ; hsa-mir-15a-3p ; hsa-mir-4740-3p ; hsa-mir-1306-5p

Nearest miRNA

hsa-mir-10226/Upstream/139201; hsa-mir-1250/Downstream/499173;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/10226, chr17-CpG: 190/Downstream/2400

Upstream sequence

CCATTCTTGATAGGATTTAAATGTTTGTTTCAATGTGCATACAAAACTAAGAAGTTCCATTAAATATACTAAGAAAAAAGCAATTTCAGCTGGACACTGT

Downstream sequence

GACCGTCATTACAAGGACAGATGATGGTGCTTCTTTCCGAAACAACTGTTCCACCGGCAGTGCAGGTCTAGCCGCTTTCCAGCGAGCCAGATAGTGGTCT