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TVIS44018071
Basic Information
VIS ID
TVIS44018071
Fusion event
HTLV-1-KRBA2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
8276984/8373666 (Hg38)
End
8276984/8373666 (Hg38)
Orient
+
Location type
Intronic
Target gene
KRBA2
miRNAs that regulate target gene
hsa-mir-5698
;
hsa-mir-6836-3p
;
hsa-mir-7641
;
hsa-mir-5001-3p
;
hsa-mir-143-5p
;
hsa-mir-4284
;
hsa-mir-3622b-5p
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-6778-3p
;
hsa-mir-6499-3p
;
hsa-mir-4695-3p
;
hsa-mir-4772-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-1304-3p
;
hsa-mir-6741-3p
;
hsa-mir-5693
;
hsa-mir-6890-3p
Nearest miRNA
hsa-mir-1253/Upstream/186662; hsa-mir-10226/Downstream/3708233;
Nearest TSS
ENST00000595228/Upstream/2126;
ENST00000579904/Downstream/2344;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/46043
,
chr17-CpG: 32/Downstream/2769
Upstream sequence
cgagattgtagcctctgcccggctgccaccccgtctgggaagtgaggagcgtctctgcctggccgcccatcgtctgggatgtgaggagcccctgtgcccg
Downstream sequence
gccgcccagtctgggaagtgaggagcctcttcccggccgccatcccgtctgggaagtgaggagggtctctgcccagccgcccatcgtctgagatgtgggg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#1
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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