Basic Information
VIS ID
TVIS44018074
Fusion event
HTLV-1-PIEZO2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
10972777/10972779 (Hg38)
End
10972777/10972779 (Hg38)
Orient
-
Location type
Intronic
Target gene
PIEZO2
Nearest miRNA
hsa-mir-3976/Upstream/213130; hsa-mir-1-2/Downstream/682106;
Nearest TSS
ENST00000575820/Upstream/79162; ENST00000591029/Downstream/175809;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/246110, chr18-CpG: 169/Downstream/175529
Upstream sequence
GATTTGGTACCATGCAAGTTCTGTAATTTCCAAATTTCATCCATGTGACTGTGCGTAatttggagacaggatttggtttggagttgcctctattaccttg
Downstream sequence
tagcagtgtatgaccttgggcaagaattaggacttctctaaTAACAGCAACAACATGAACAACAGCTTGTACTATttgaccacttacaatgggtcaagca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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