Basic Information
VIS ID
TVIS44018122
Fusion event
HTLV-1-chr18 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
54968326/57301095 (Hg38)
End
54968326/57301095 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA18B
Nearest miRNA
hsa-mir-1-2/Upstream/1821797; hsa-mir-122/Downstream/1149979;
Nearest TSS
ENST00000575820/Upstream/129901; ENST00000324000/Downstream/49718;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/179132, chr18-CpG: 154/Downstream/51381
Nearby gene
ST8SIA3(+51395) ;
Upstream sequence
accactatccctattttatagctcaggaaattcatgtctagaaaggtttagcccctgcccagggccacaacagttctaagtagaaggcgaagatataaac
Downstream sequence
ccaaccatgtctgactcgactctgtgctttcagccatcacaccctgctgcttcCTGAAAGTCTTtggtcacatcagtttgagaattgccggcttaaccga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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