Basic Information
VIS ID
TVIS44018153
Fusion event
HTLV-1-chr19 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.13
Reference genome
GRCh37/hg19
Start
12899570/12788756 (Hg38)
End
12899570/12788756 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA19B
Nearest miRNA
hsa-mir-10395/Upstream/1564; hsa-let-7e/Downstream/63504;
Nearest TSS
ENST00000633603/Upstream/3655; ENST00000302754/Downstream/2740;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5474, chr19-CpG: 365/Downstream/834
Nearby gene
JUNB(+2740) ;
Nearest cancer related gene
JUNB(OG, +2740) ;
Upstream sequence
TGGCTTTTGGGACCTGCAAGTTAGCTTCCCAAGGTGCTGCCCTCTGGCCTGCCCTGCCCTGCCCAACCCCCCAACGCTGCCCGCTGCGCCCCCGCGGGGC
Downstream sequence
CCAGCCAGATGTCAGCTGCAGTTATTAGCCTGGGCGGGAGACACAGGCCTGGCAGTGTGCCTGCCAGACTCACAGGCCTCCGGAATCTCCCTTGAGCCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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