Basic Information
VIS ID
TVIS44018158
Fusion event
HTLV-1-PODNL1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.12
Reference genome
End
14043870/13933057 (Hg38)
Orient
+
Location type
Exonic
Fragile sites / regions
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-10395/Upstream/58046; hsa-let-7e/Downstream/140304;
Nearest CpG islands
chr19-CpG: 53/Target, None/Upstream, None/Downstream
Upstream sequence
GTGGGCAGGCCCATGGGCAGCCGGGTTAGCTGATTCCCTGCCAGGTCGAGGCTGCGCAGGGCACGCAACCGGCGGAAGGCCCGGTGGTGCACACGGGCGC
Downstream sequence
TGGCCAGGCGGTTATAGGCCAGGTTAAGCTCCGTCAGGCCCGGTGTGGCGACCAGGTCACGGGCACCCAGCGCGGCCACGTGGTTGTGGGGCAGCACCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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