Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene178753701774771817788568177948281781308217794006177998061776429517767381177900961779244117775432177772761777821217779816177700731777134917762179177632411776740617768339178032011780389117802216178028421778400017784469177881501778860417806835178072851778755717787950177801671778047017784472177846411779263217792781177929121779293217811544
Basic Information
VIS ID
TVIS44018166
Fusion event
HTLV-1-B3GNT3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.11
Reference genome
GRCh37/hg19
Start
17922353/17811544 (Hg38)
End
17922353/17811544 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
B3GNT3
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-10395/Upstream/2361936; hsa-let-7e/Downstream/470533;
Nearest TSS
ENST00000633603/Upstream/16387; ENST00000602216/Downstream/9961;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/3255, chr19-CpG: 40/Downstream/9598
Upstream sequence
GCCTTAACCCAGGCTGGATTGTGGACACTTCCTTTCCTGGGCTTAGTGGGCTGGAGTGGCTAATAGAGACCCAAGGCCAATTTCTCCAGCCCTCAAGCAA
Downstream sequence
GCATGCCCTGTCCACCCTGCCTGCAGGTCCTGTTCTTACAGTGGCAGGAGACAAGGTGCGCCAACGCCAGCTTCGTGCTCAACGGGGATGATGACGTCTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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