VISDB Viral Integration Site DataBase

VIS ID

TVIS44018184

Fusion event

HTLV-1-CEP89 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

q13.11

Reference genome

Start

End

33415113/32924207 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193a-3p ; hsa-mir-6842-3p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-3922-3p ; hsa-mir-3176 ; hsa-mir-4433a-3p ; hsa-mir-6504-3p ; hsa-mir-889-5p ; hsa-mir-4433b-3p ; hsa-mir-4700-3p ; hsa-mir-7153-3p ; hsa-mir-6749-3p ; hsa-mir-1260b ; hsa-mir-1260a ; hsa-mir-532-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-1224-3p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-6513-3p ; hsa-mir-4714-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-5698 ; hsa-mir-7156-3p ; hsa-mir-143-5p ; hsa-mir-3622b-5p ; hsa-mir-6499-3p ; hsa-mir-1184 ; hsa-mir-1304-3p ; hsa-mir-103b ; hsa-mir-5693 ; hsa-mir-6890-3p ; hsa-mir-7705 ; hsa-mir-6854-5p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-656-5p ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6765-3p

Nearest miRNA

hsa-mir-10395/Upstream/12524853; hsa-let-7e/Downstream/2198493;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/203033, chr19-CpG: 48/Downstream/47602

Upstream sequence

cgatcctcccacctcagcttcccaagtacctgtactactatgcctggctaatttttgtattttgtgtatagacgaggtttcgccatgttactcaaggctg

Downstream sequence

ctcttgaactcctaggctcaaggaatcttcctgcctcagactcccaaaatgctgggattacagtcatgagtcaccacatccagccAAGGCTCTTAGTTTT