VISDB Viral Integration Site DataBase

VIS ID

TVIS44018192

Fusion event

HTLV-1-CAPNS1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

q13.12

Reference genome

Start

End

36634021/36143119 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-744-5p ; hsa-mir-296-3p ; hsa-mir-769-5p ; hsa-mir-193b-3p ; hsa-mir-425-3p ; hsa-mir-320a ; hsa-mir-183-5p ; hsa-mir-100-5p ; hsa-mir-99a-5p ; hsa-mir-7106-3p ; hsa-mir-331-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-491-5p ; hsa-mir-100-3p ; hsa-mir-125a-3p ; hsa-mir-1278 ; hsa-mir-1289 ; hsa-mir-1291 ; hsa-mir-185-5p ; hsa-mir-2467-5p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3192-5p ; hsa-mir-3198 ; hsa-mir-3199 ; hsa-mir-3925-5p ; hsa-mir-4260 ; hsa-mir-4265 ; hsa-mir-4292 ; hsa-mir-4294 ; hsa-mir-4296 ; hsa-mir-4306 ; hsa-mir-4309 ; hsa-mir-4322 ; hsa-mir-4508 ; hsa-mir-4515 ; hsa-mir-4644 ; hsa-mir-4721 ; hsa-mir-4793-5p ; hsa-mir-5090 ; hsa-mir-5196-3p ; hsa-mir-6075 ; hsa-mir-6727-5p ; hsa-mir-6731-5p ; hsa-mir-6749-3p ; hsa-mir-6758-5p ; hsa-mir-6759-5p ; hsa-mir-6761-5p ; hsa-mir-6775-3p ; hsa-mir-6775-5p ; hsa-mir-6788-5p ; hsa-mir-6791-5p ; hsa-mir-6793-5p ; hsa-mir-6796-5p ; hsa-mir-6856-5p ; hsa-mir-6878-5p ; hsa-mir-7160-3p ; hsa-mir-8052 ; hsa-mir-8085

Nearest miRNA

hsa-mir-10395/Upstream/797492; hsa-let-7e/Downstream/3266504;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/2879, chr19-CpG: 85/Downstream/8306

Upstream sequence

AGGATTTGACCTCTGGCCTCTGACTTTCAACCTGTTACCCACAGACCCTGATCTGAAGACTGATGGTTTTGGCATTGACACATGTCGCAGCATGGTGGCC

Downstream sequence

GTGATGGATGTATCCTTGGGGGCAGTGTGGGAGAGGCCCTGGGTGGACAGAGAGTTTTTTGAGAGTATGTTTGGGAAGCCAACATGTAGCTTTCATATCC