VISDB Viral Integration Site DataBase

VIS ID

TVIS44018199

Fusion event

HTLV-1-ZBTB7A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

4058915/4058917 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-222-3p ; hsa-mir-93-5p ; hsa-mir-4329 ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-let-7f-2-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-4668-3p ; hsa-mir-139-3p ; hsa-mir-1915-3p ; hsa-mir-548t-5p ; hsa-mir-3175 ; hsa-mir-3184-3p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-548az-5p ; hsa-mir-6764-5p ; hsa-mir-6795-5p ; hsa-mir-6870-5p ; hsa-mir-6887-5p ; hsa-mir-7111-5p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-513a-3p ; hsa-mir-590-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-1470 ; hsa-mir-4469 ; hsa-mir-4667-3p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-6515-5p ; hsa-mir-4443 ; hsa-mir-1200 ; hsa-mir-6879-3p ; hsa-mir-6848-5p ; hsa-mir-6846-5p ; hsa-mir-5010-5p ; hsa-mir-4525 ; hsa-mir-185-3p ; hsa-mir-4656 ; hsa-mir-4713-3p ; hsa-mir-4524a-3p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-500b-3p ; hsa-mir-4323 ; hsa-mir-6819-5p ; hsa-mir-6812-5p ; hsa-mir-6737-5p ; hsa-mir-6742-5p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6747-5p ; hsa-mir-4664-5p ; hsa-mir-342-5p ; hsa-mir-6825-5p ; hsa-mir-4649-5p ; hsa-mir-6729-5p ; hsa-mir-6089 ; hsa-mir-6886-5p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6863 ; hsa-mir-877-3p ; hsa-mir-374a-3p ; hsa-mir-361-5p ; hsa-mir-4286 ; hsa-mir-153-5p ; hsa-mir-4328 ; hsa-mir-5094 ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-4435 ; hsa-mir-608 ; hsa-mir-4651 ; hsa-mir-4768-3p ; hsa-mir-665 ; hsa-mir-216b-5p ; hsa-mir-216a-5p ; hsa-mir-372-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4484 ; hsa-mir-371a-5p ; hsa-mir-335-3p ; hsa-mir-664b-3p ; hsa-mir-5696 ; hsa-mir-579-3p ; hsa-mir-374b-5p ; hsa-mir-4775 ; hsa-mir-374a-5p ; hsa-mir-1250-3p ; hsa-mir-6868-3p ; hsa-mir-4423-5p ; hsa-mir-656-5p ; hsa-mir-4790-5p ; hsa-mir-3615 ; hsa-mir-4315 ; hsa-mir-6812-3p ; hsa-mir-8070 ; hsa-mir-4796-5p ; hsa-mir-2277-5p ; hsa-mir-4479 ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-6889-5p ; hsa-mir-4501 ; hsa-mir-3163 ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-4795-3p ; hsa-mir-6083 ; hsa-mir-126-5p ; hsa-mir-656-3p ; hsa-mir-410-3p ; hsa-mir-1277-5p ; hsa-mir-4742-3p ; hsa-mir-100-5p ; hsa-mir-520e ; hsa-mir-125a-5p ; hsa-mir-1207-5p ; hsa-mir-130a-3p ; hsa-mir-130b-3p ; hsa-mir-194-3p ; hsa-mir-296-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3591-5p ; hsa-mir-3666 ; hsa-mir-3677-5p ; hsa-mir-4264 ; hsa-mir-4295 ; hsa-mir-4473 ; hsa-mir-454-3p ; hsa-mir-4671-3p ; hsa-mir-4763-3p ; hsa-mir-4797-3p ; hsa-mir-5693 ; hsa-mir-629-5p ; hsa-mir-6823-5p

Nearest miRNA

hsa-mir-1227/Upstream/97405; hsa-let-7e/Downstream/387061;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/3626, chr19-CpG: 19/Downstream/1002

Nearest cancer related gene

ZBTB7A(OG, No orient, 0)

Upstream sequence

GACACAGAGGCCTTTGTGAGCTTGCTCAGTGCCACCACGCTCCCCAGGCCCCTCCACCCGCCTTCCTTCCCTCCTTCCAGCCTCGGCCCAGGGCCCAGCT

Downstream sequence

GCTCAGCACCCCCGTCTACTCTAAGGCCTGTGGTGGGGCGGTGGGCTCAGATGTGGCTGCTGGGAGCAGGGAGGGTAGGAGGGGAGCGACCCCACCCAAG