Basic Information
VIS ID
TVIS44018218
Fusion event
HTLV-1-LOC107985342 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
54166064/53662810 (Hg38)
End
54166064/53662810 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
LOC107985342
Nearest miRNA
hsa-let-7e/Upstream/1380917; hsa-mir-10394/Downstream/3869;
Nearest TSS
ENST00000633603/Upstream/30754; ENST00000597619/Downstream/99151;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/13823, chr19-CpG: 23/Downstream/105676
Nearby gene
MIR512-2(+3863) ;
Upstream sequence
cttgaggccaggagttcgagaccaggctggctaacatggtgaaaccccatctctactaaaaataaaaaaattagccaggcatggtggtgcgcgcctgtaa
Downstream sequence
tcccagtgactcgggaggctgaggcaggtgaatcacttgacccctggaggcagaggctgcagtgagccaagatcataccactgcactctagcctggacaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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