VISDB Viral Integration Site DataBase

VIS ID

TVIS44018226

Fusion event

HTLV-1-ARID3A integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr19

Cytoband

p13.3

Reference genome

Start

End

928513/928513 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-let-7b-5p ; hsa-mir-30b-5p ; hsa-mir-98-5p ; hsa-let-7d-5p ; hsa-mir-484 ; hsa-mir-425-3p ; hsa-mir-125b-5p ; hsa-mir-30a-5p ; hsa-mir-148a-3p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-152-3p ; hsa-mir-30e-5p ; hsa-mir-148b-3p ; hsa-mir-3171 ; hsa-mir-6757-5p ; hsa-mir-8485 ; hsa-let-7c-5p ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6836-5p ; hsa-mir-6132 ; hsa-mir-202-3p ; hsa-mir-4500 ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-mir-4458 ; hsa-let-7i-5p ; hsa-let-7a-5p ; hsa-let-7e-5p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-6083 ; hsa-mir-4753-3p ; hsa-mir-130b-5p ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-660-3p ; hsa-mir-5193 ; hsa-mir-7856-5p ; hsa-mir-556-3p ; hsa-mir-6809-3p ; hsa-mir-99b-5p ; hsa-mir-125a-5p ; hsa-mir-129-5p ; hsa-mir-3140-3p ; hsa-mir-6885-3p

Nearest miRNA

hsa-mir-1302-11/Upstream/114860; hsa-let-7e/Downstream/887646;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/1643, chr19-CpG: 45/Downstream/844

Nearest cancer related gene

ARID3A(OG, No orient, 0)

Upstream sequence

TGAGTGTGTTGCCGTCCGAGACATCTGGCCCACTCGGGATCCCAGAGGACCGGGAAACTCCAGACCCCTGTTGCCCTGCAGAGATTGTGGGGTCTGCGTG

Downstream sequence

GGAggctctgtggtcacccagacctgggttcaaatcccaccgccatgtctccaagcagaggatccctgagcctcagttgtcctcaaccatgaaatgggAC