Basic Information
VIS ID
TVIS44018237
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.23
Reference genome
GRCh37/hg19
Start
18870061/18889417 (Hg38)
End
18870061/18889417 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA20A
Nearest miRNA
hsa-mir-103a-2/Upstream/418726; hsa-mir-1-1/Downstream/7318769;
Nearest TSS
ENST00000382410/Upstream/75691; ENST00000613834/Downstream/167379;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/300969, chr20-CpG: 155/Downstream/322398
Nearby gene
C20orf78(No orient, 59214)
Upstream sequence
TTGTCATCAGGAAATCAGTATCTCCTACTCACAAAACTTGCAGGGCTAATTTCTGTGGTAGTCTGCACAAATTTAGCCAAGAAAATCAAATTTCCACTAT
Downstream sequence
CCCGAGAAGGTTAGCTCTGTTGTTGAAATTATTATAATCACTTAGTTTAAGGGGTGAGTTTTTAAGAACCACTTCTCCTTTACCAAGGCAGACAGAGCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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