Basic Information
VIS ID
TVIS44018245
Fusion event
HTLV-1-LOC105372568 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
22797473/22816835 (Hg38)
End
22797473/22816835 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105372568
Nearest miRNA
hsa-mir-103a-2/Upstream/4346144; hsa-mir-1-1/Downstream/3391351;
Nearest TSS
ENST00000382410/Upstream/131371; ENST00000255008/Downstream/213950;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/229593, chr20-CpG: 117/Downstream/218244
Upstream sequence
AATTGAGGTCACGCTTAAAGAGAGATAATTCACAGTGATTTAAATGAATGCTACACAAAACATGGGCCTGAATTTCatatatatatatatatatatatat
Downstream sequence
atatatatatGTGCATGCTTTAAGTTAAAGTGAAAAAAGACCATAGCATTTTTCTTTATTTTTTTGAAAGAGAACCATATTTAATTTTATCTTAATGTAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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