Basic Information
VIS ID
TVIS44018251
Fusion event
HTLV-1-FAM242A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
29559287/30324611 (Hg38)
End
29559287/30324611 (Hg38)
Orient
-
Location type
ncRNA_exonic
Target gene
FAM242A
Nearest miRNA
hsa-mir-103a-2/Upstream/4116333; hsa-mir-1-1/Downstream/1282575;
Nearest TSS
ENST00000382410/Upstream/36132; ENST00000400552/Downstream/11076;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/7432, chr20-CpG: 73/Downstream/52112
Upstream sequence
TCCCCAGAactttacctctcttggccgcagtcttctcatctgtaaaatgaggataagatactaggaggggttgagggtccgggaaggtttaatgagacag
Downstream sequence
cttgtcagtgaccagcacagGGTAGGTCCCCAGCAGTGGCTGCTTCCTTCTCTGTAGTCTAACCATGAGCCTTCCTGCTGTGCCTTCCTGCGCTGCCTCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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