Basic Information
VIS ID
TVIS44018262
Fusion event
HTLV-1-ADA integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
43275506/44646865 (Hg38)
End
43275506/44646865 (Hg38)
Orient
+
Location type
Intronic
Target gene
ADA
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-484 ; hsa-mir-140-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/238662; hsa-mir-1-1/Downstream/778645;
Nearest TSS
ENST00000382410/Upstream/20374; ENST00000497421/Downstream/4796;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/114689, chr20-CpG: 83/Downstream/4555
Upstream sequence
ccaccctgATTCTAACTCTTCCCCCCACACTGCCCCCTCTTTTTTGCATAAAGTGGAATTGGCAAATGagcaaagcaatgaacagcttctacttgagtgc
Downstream sequence
aggcagatctgggttcaagtctagctctgctgcttgccagctgtgtgactttggcaagttccctcccctctctgagtctcagtttcctcataataagtga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate