Basic Information
VIS ID
TVIS44018269
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
47213576/48597038 (Hg38)
End
47213576/48597038 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/1429980; hsa-mir-1-1/Downstream/1266821;
Nearest TSS
ENST00000382410/Upstream/120039; ENST00000493140/Downstream/45700;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/211811, chr20-CpG: 24/Downstream/39358
Nearby gene
PREX1(-27217) ;
Upstream sequence
gaaagggagaacaaaattggaggaagtcagcagtctcttccaTTCTGTACATGAATGTTTGCACAGGTGAGGCCCCTAGGTGTATTGTGGGAATGTGTCC
Downstream sequence
ACACCTGTGTTGGAAGCATTGTTCACCATCAGTTATTAAGCATCCACTCAAGAAATTCTGCTGTGTAAGAAAATGCATGGATAATAAATGCATATGGGCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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