Basic Information
VIS ID
TVIS44018278
Fusion event
HTLV-1-chr20 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
57359468/58784412 (Hg38)
End
57359468/58784412 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-103a-2/Upstream/1462821; hsa-mir-1-1/Downstream/33203;
Nearest TSS
ENST00000382410/Upstream/30061; ENST00000306120/Downstream/33313;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/28030, chr20-CpG: 24/Downstream/55128
Nearby gene
MIR296(-33202) ;
Nearest cancer related gene
MIR296(TSG, -33202) ;
Upstream sequence
GTGACCTTATTGATAAATGCAAGTGGTCTCCCAGCGGTTTCTCCTGGGACCTCTACCATCACCCTGTGATGCTAGGAGCTGCCCACCCTGTGTGAGAGCA
Downstream sequence
GGAACCAGAAGGCAGACGGGACAGAGGAGGGCTGGGGCCAGCCCTGCAAGTCCAGCTCCCCAGCCAGCGTGGGGCTATGCTTTCTAAGCCGTGTCCCCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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