Basic Information
VIS ID
TVIS44018287
Fusion event
HTLV-1-CDH4 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
End
60415296/61840240 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-103a-2/Upstream/1275615; hsa-mir-1-1/Downstream/113306;
Nearest cancer related gene
CDH4(TSG, No orient, 0)
Upstream sequence
CCTAATTCTGAGAGTGTCTGTGTCCGTCTGCGGGCTGACTGAGAGAGACCTTCCCGACCGTGCACGTGCACTGGGACAGCTCTGGCTGACAGGAGGCCCT
Downstream sequence
GGTGCAGGGGCCTTCCCGGTGGGTGGGTCTCTCCCTCCCCCAGAATCTGGGTGTAACTCTCTCTCCCCGGCTTCCACCCTTGAAAGCTTAGGGAATCCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate