Basic Information
VIS ID
TVIS44018290
Fusion event
HTLV-1-LINC01428 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
7149305/7168658 (Hg38)
End
7149305/7168658 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LINC01428
Nearest miRNA
hsa-mir-103a-2/Upstream/3251087; hsa-mir-1-1/Downstream/202950;
Nearest TSS
ENST00000382410/Upstream/99044; ENST00000455299/Downstream/85544;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/398348, chr20-CpG: 96/Downstream/850484
Upstream sequence
AGTGTATTCTCTGGGTGCTTCTCATCCATTCAAACCTTCATTTAGTGAAATTCCATGAAATTTTAATGAAATAAATATAATGACAGCAGGCATATTTCCC
Downstream sequence
CACCCTAATTTTCCCCCAAACTGACGTGTTAGAAGATGACTTCATGGATATTTATTTGATGTTAGAGGTATGGGATTTGGATTTTGAAAGTTTATGTTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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