Basic Information
VIS ID
TVIS44018295
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
11109567/10402888 (Hg38)
End
11109567/10402888 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10396a/Upstream/1415223; hsa-let-7c/Downstream/3003496;
Nearest TSS
ENST00000624081/Upstream/60151; ENST00000612957/Downstream/118665;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/283948, chr21-CpG: 27/Downstream/2588
Upstream sequence
ggtggaggctggtggatcacttgaggtctggagttcaagaccagcctggccaacatggtgaaaccccatctctactaaaaataaaaaaCTAggccgggca
Downstream sequence
ccatggctcacgcctgtaatcccagcactttgggaggccgacatgggtggatcacgaggtcaggagatggagaccatcctggctaacacagtgaaaccct
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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