Basic Information
VIS ID
TVIS44018300
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
17087229/15714910 (Hg38)
End
17087229/15714910 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA21A
Nearest miRNA
hsa-mir-10396a/Upstream/1990636; hsa-let-7c/Downstream/824179;
Nearest TSS
ENST00000624081/Upstream/87568; ENST00000464435/Downstream/15115;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/649367, chr21-CpG: 123/Downstream/14624
Nearby gene
USP25(+15115) ;
Upstream sequence
ATTAGAAAAAATGTCCTGATGTACTAAGCAGTCCATAAGAACTCTAGTTTAAATGACCAAAAGAAATGTAAACTTAGAATGGCAGGTAAATTTGGGTTGG
Downstream sequence
TAGGTAAGGATTAAAAGAATTTGGATTTGATGGAATCTTTTTAAAGCAGTCTGGGTCTAGCATGGAACTACCCCTAAAGAATATTGGAAGAGTCTggccg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate