Basic Information
VIS ID
TVIS44018309
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
24629943/23257621 (Hg38)
End
24629943/23257621 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7c/Upstream/178229; hsa-mir-155/Downstream/2316359;
Nearest TSS
ENST00000624081/Upstream/192130; ENST00000433101/Downstream/127240;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/2259376, chr21-CpG: 28/Downstream/2104173
Nearby gene
D21S2088E(-103483) ;
Upstream sequence
CCCTACCAATCTTATATTTATTTTAAGCCCTCCAAAATTGCTACCAATCATAACGATGAAGATGTTCAGACTCATTGATTTTCATTCCTTAATATTATtg
Downstream sequence
tattagccagggttctctggagagacagaactaataggatatatatatacacacacacacacacacacacacacacacacacacacacacacatatacac
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate