Basic Information
VIS ID
TVIS44018310
Fusion event
HTLV-1-LOC105372750 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
25229591/23857275 (Hg38)
End
25229591/23857275 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105372750
Nearest miRNA
hsa-let-7c/Upstream/777883; hsa-mir-155/Downstream/1716705;
Nearest TSS
ENST00000624081/Upstream/379634; ENST00000415269/Downstream/33266;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/2859030, chr21-CpG: 28/Downstream/1504519
Upstream sequence
agtcttgctgctgctcagtatttgggtctgcgctacctttatgagctgtagcactccccacgaaggtctgcagcttcactcctgaagccagcaacaccac
Downstream sequence
gaacctaccgggaggaacaaacaactccagaggcaccaccattaagagctgttaacactcactgcgaaggtctccggcttcactcctgaagtcagtgaga
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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