Basic Information
VIS ID
TVIS44018320
Fusion event
HTLV-1-MIS18A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
q22.11
Reference genome
End
33637162/32264851 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7c/Upstream/1889473; hsa-mir-3197/Downstream/1285811;
Nearby gene
MIS18A(-3368) ;
Upstream sequence
CTGCAACGGGTCCCTCTCCTGGTCTTGAGCATTTTAAATGTCCCATGCTTGACTAGAATCATCCGGGTAGGACACATGCCATTCAGGCATCGATGCTACA
Downstream sequence
CAGAATGGTGCCTCCAGTGGACTCTTTAGCTTGGAAATGTATGAGCATGACTGGAGAACTTGCCAAGGACAGCACCCACACTCTGGGATGAAAAACAGGC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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