Basic Information
VIS ID
TVIS44018339
Fusion event
HTLV-1-chr21 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr21
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
9863474/9024641 (Hg38)
End
9863474/9024641 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10396a/Upstream/36976; hsa-let-7c/Downstream/4381743;
Nearest TSS
ENST00000624081/Upstream/5971; ENST00000624052/Downstream/300372;
Nearest CpG islands
None/Target, chr21-CpG: 261/Upstream/36663, chr21-CpG: 20/Downstream/45537
Nearby gene
LOC105372731(+1972) ;
Upstream sequence
ctgggagcttgccaattacacaaagacagaaggcatgtgtgctggaccttgcatgcttatctgttcaggacttatctgtaggtgcagtagttgtgatttt
Downstream sequence
tcaggctgacagcttccctgaggaccagtctcttacttgtttactcaactaattttcctttccttctccctcaACATTATGCAGCAAAACAGAGTACACT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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