Basic Information
VIS ID
TVIS44018346
Fusion event
HTLV-1-LOC105372861 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
19719307/19731784 (Hg38)
End
19719307/19731784 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105372861
Nearest miRNA
hsa-mir-3198-1/Upstream/1750823; hsa-let-7a-3/Downstream/231969;
Nearest TSS
ENST00000624155/Upstream/8839; ENST00000475303/Downstream/24919;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/556, chr22-CpG: 19/Downstream/4984
Nearby gene
SEPT5-GP1BB(+7010) ;
Upstream sequence
AGATGGGGACCGAGACAGAGATGGGAGCCAGGTCTAGAGGAGAGACCAGAGACAGTGGCACTGTGGTGGCCCCGTTGACACGGGCCAGGACCCTTGCTTG
Downstream sequence
GGTGTCTGGCCTCCCCGCTCTGGGCGCCCCTTCCACAAAGCCCATCTGGAAACCAGCTGAGAGCCACCGTACCCCCACCCCGGCTGACCCCCAACAGGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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