Basic Information
VIS ID
TVIS44018351
Fusion event
HTLV-1-GGTLC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
22989452/22646982 (Hg38)
End
22989452/22646982 (Hg38)
Orient
+
Location type
splicing
Target gene
GGTLC2
Nearest miRNA
hsa-mir-1286/Upstream/993597; hsa-let-7a-3/Downstream/175794;
Nearest TSS
ENST00000624155/Upstream/636; ENST00000520084/Downstream/14317;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/2239, chr22-CpG: 142/Downstream/423063
Upstream sequence
TATGGGGTGGAGGTCTGGGGATGGGGGACTGGGGTGGAGAGGGGCGGGTGTCCTGGGCAGGCAGCTGACGGGCATCCCTGTCTTCTCCCATCGGCCACAG
Downstream sequence
GGAAGCAGCCGCTCTCGTCAATGTGCCCGACGATCATGGTGGGCCAGGACGGCCAGGTCCGGATGGTGGTGGGAGCTGCTGGGGGCACACAGATCACCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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