Basic Information
VIS ID
TVIS44018352
Fusion event
HTLV-1-IGL integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q11.22
Reference genome
GRCh37/hg19
Start
23076709/22734221 (Hg38)
End
23076709/22734221 (Hg38)
Orient
+
Location type
Intronic
Target gene
IGL
Nearest miRNA
hsa-mir-1286/Upstream/1080836; hsa-let-7a-3/Downstream/88555;
Nearest TSS
ENST00000624155/Upstream/13598; ENST00000390310/Downstream/386;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/89478, chr22-CpG: 142/Downstream/335824
Nearby gene
GGTLC2(+86341) ;
Upstream sequence
GGGACGAGGCTGCAGCTGTGGAGACCAGGGACCCATGATGCCCAGCAGAGGTTTCCACGGGGTGGGTAGCCCCATTTCCTGACAGTAGAGACAGCCTAGA
Downstream sequence
GGTGGGTGCCAAGCAGAGGGCACTGTGCCATGTGCCCAGGCCTGGAGGGCCACAGAGACACAGGCGCCACACAGCAGAGACACTGAGAGCCAGGAGCTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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