VISDB Viral Integration Site DataBase

VIS ID

TVIS44018375

Fusion event

HTLV-1-RBFOX2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q12.3

Reference genome

Start

End

36366549/35970501 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-320d ; hsa-mir-498 ; hsa-mir-9-5p ; hsa-mir-32-5p ; hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-186-5p ; hsa-let-7a-5p ; hsa-mir-3923 ; hsa-mir-432-3p ; hsa-mir-432-5p ; hsa-mir-106a-3p ; hsa-mir-203b-3p ; hsa-mir-7154-5p ; hsa-mir-4755-3p ; hsa-mir-628-3p ; hsa-mir-8060 ; hsa-mir-4650-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-25-3p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-921 ; hsa-mir-1294 ; hsa-mir-630 ; hsa-mir-202-3p ; hsa-mir-3163 ; hsa-mir-3174 ; hsa-mir-548l ; hsa-mir-3133 ; hsa-mir-548n ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7f-5p ; hsa-let-7g-5p ; hsa-let-7i-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-mir-98-5p ; hsa-mir-4272 ; hsa-mir-6074 ; hsa-mir-7109-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-4326 ; hsa-mir-6885-5p ; hsa-mir-328-5p ; hsa-mir-6887-5p ; hsa-mir-6795-5p ; hsa-mir-637 ; hsa-mir-4729 ; hsa-mir-136-5p ; hsa-mir-548e-5p ; hsa-mir-1253 ; hsa-mir-3928-5p ; hsa-mir-449b-3p ; hsa-mir-6770-5p ; hsa-mir-6806-3p ; hsa-mir-6854-5p ; hsa-mir-1910-3p ; hsa-mir-3148 ; hsa-mir-3714 ; hsa-mir-4484 ; hsa-mir-548an ; hsa-mir-6511a-5p ; hsa-mir-651-3p ; hsa-mir-6768-3p

Nearest miRNA

hsa-mir-1286/Upstream/633702; hsa-let-7a-3/Downstream/316346;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/418552, chr22-CpG: 131/Downstream/57670

Upstream sequence

actttgggaggctgaggcaggaggactgctcaaggtcaggagctcaagaccagcctgggcaatacagtgagacccatctcaaaaaaaaaaaaaacacaca

Downstream sequence

cactcttcaattaaccaggcatgctggcatgtacctgtagtcccagctactttggagactgaggtaggaggattgcttgagcccaggagctcgggactgc