VISDB Viral Integration Site DataBase

VIS ID

TVIS44018376

Fusion event

HTLV-1-ELFN2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q13.1

Reference genome

Start

End

37787877/37391837 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1200 ; hsa-mir-1207-5p ; hsa-mir-1225-3p ; hsa-mir-1226-5p ; hsa-mir-1249-5p ; hsa-mir-1250-5p ; hsa-mir-1321 ; hsa-mir-134-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-1909-3p ; hsa-mir-1910-3p ; hsa-mir-214-3p ; hsa-mir-3064-3p ; hsa-mir-3118 ; hsa-mir-3126-5p ; hsa-mir-3136-5p ; hsa-mir-3141 ; hsa-mir-3151-3p ; hsa-mir-3164 ; hsa-mir-3202 ; hsa-mir-3619-5p ; hsa-mir-3653-5p ; hsa-mir-3915 ; hsa-mir-3928-3p ; hsa-mir-4252 ; hsa-mir-4261 ; hsa-mir-4291 ; hsa-mir-4300 ; hsa-mir-4302 ; hsa-mir-4317 ; hsa-mir-4324 ; hsa-mir-4419a ; hsa-mir-4439 ; hsa-mir-4476 ; hsa-mir-4510 ; hsa-mir-4513 ; hsa-mir-4519 ; hsa-mir-4688 ; hsa-mir-4715-3p ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4746-3p ; hsa-mir-4747-5p ; hsa-mir-4756-5p ; hsa-mir-4763-3p ; hsa-mir-486-3p ; hsa-mir-494-3p ; hsa-mir-512-5p ; hsa-mir-5196-5p ; hsa-mir-544b ; hsa-mir-558 ; hsa-mir-5591-5p ; hsa-mir-595 ; hsa-mir-6087 ; hsa-mir-6090 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-615-5p ; hsa-mir-636 ; hsa-mir-644a ; hsa-mir-6499-3p ; hsa-mir-6511a-5p ; hsa-mir-663b ; hsa-mir-6721-5p ; hsa-mir-6722-3p ; hsa-mir-6726-5p ; hsa-mir-6731-5p ; hsa-mir-6734-5p ; hsa-mir-6743-5p ; hsa-mir-6755-5p ; hsa-mir-6760-5p ; hsa-mir-6783-5p ; hsa-mir-6785-5p ; hsa-mir-6797-5p ; hsa-mir-6820-3p ; hsa-mir-6824-5p ; hsa-mir-6827-5p ; hsa-mir-6834-5p ; hsa-mir-6855-3p ; hsa-mir-6857-3p ; hsa-mir-6871-5p ; hsa-mir-6875-5p ; hsa-mir-6876-5p ; hsa-mir-6883-5p ; hsa-mir-7108-5p ; hsa-mir-7112-5p ; hsa-mir-7515 ; hsa-mir-761 ; hsa-mir-8085 ; hsa-mir-920 ; hsa-mir-922 ; hsa-mir-9500 ; hsa-mir-4691-5p ; hsa-mir-6792-3p

Nearest miRNA

hsa-mir-1286/Upstream/1104930; hsa-let-7a-3/Downstream/452435;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/16433, chr22-CpG: 66/Downstream/27927

Upstream sequence

acggcagacagacccttacatgacagggagagaaactgaggctctgagaaatgacctgtgcccagccccaggcctggcaaatattggaaagggccttccc

Downstream sequence

aggcagtGCGTGGGTCCCACATCCTCTGAGACTCAGGAGGAAGGGGTGCagacctgggcctgagcccaactggccctcgcgtggctgggtgacatgggca