Basic Information
VIS ID
TVIS44018383
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41757982/41361978 (Hg38)
End
41757982/41361978 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-mir-1281/Upstream/108928; hsa-let-7a-3/Downstream/538966;
Nearest TSS
ENST00000624155/Upstream/60263; ENST00000413942/Downstream/5355;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/15817, chr22-CpG: 97/Downstream/19408
Nearby gene
ZC3H7B(+1831) ;
Upstream sequence
AGATCGCGTGCCTGCATCAAGACCTTACAggattactcctgtaatcctgccttgggagatcaaggcaggaggatcacttgaggccaggagcttgagacta
Downstream sequence
gcctgagcaacagtaaagccgtatctctacaaaaaaaaaaaaaaaaagtaaaattagctgggtatggtggtccacacctgtggtcctagctacttgggag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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