VISDB Viral Integration Site DataBase

VIS ID

TVIS44018390

Fusion event

HTLV-1-PNPLA3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr22

Cytoband

q13.31

Reference genome

Start

End

44342120/43946240 (Hg38)

Orient

+

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-4701-5p ; hsa-mir-5010-3p ; hsa-mir-2113 ; hsa-mir-5096 ; hsa-mir-197-3p ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-6832-5p ; hsa-mir-4524a-3p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-4735-5p ; hsa-mir-6823-5p ; hsa-mir-6765-3p ; hsa-mir-1228-3p ; hsa-mir-4524b-3p ; hsa-mir-590-3p ; hsa-mir-4279 ; hsa-mir-656-5p ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-7113-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4308 ; hsa-mir-8062 ; hsa-mir-6878-3p ; hsa-mir-4727-5p ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-5189-3p ; hsa-mir-6817-5p ; hsa-mir-4769-3p ; hsa-mir-150-5p ; hsa-mir-212-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6813-3p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6513-3p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-4763-5p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-130b-5p ; hsa-mir-6504-3p ; hsa-mir-4687-5p ; hsa-mir-4438 ; hsa-mir-1289 ; hsa-mir-129-5p ; hsa-mir-1304-5p ; hsa-mir-3198 ; hsa-mir-4294 ; hsa-mir-4309 ; hsa-mir-6134 ; hsa-mir-6880-5p ; hsa-mir-7854-3p ; hsa-mir-8055

Nearest miRNA

hsa-mir-1281/Upstream/2022943; hsa-let-7a-3/Downstream/1254714;

Nearest TSS

Nearest CpG islands

None/Target, chr22-CpG: 279/Upstream/21607, chr22-CpG: 71/Downstream/8782

Upstream sequence

CCATGTGTTTCAGGTCCCAAATGCCAGTGAGCAGCCAACAGGCCTCCCCATGCACACCTGAGCAGGACTGGCCCTGCTGGACTCCCTGCTCCCCCAAGGG

Downstream sequence

CTGTCCAGCAGAGACCAAAGCAGAGGCCACCCCGCGGTCCATCCTCAGGTCCAGCCTGAACTTCTTCTTGGGCAATAAAGTACCTGCTGGTGCTGAGGGG