Basic Information
VIS ID
TVIS44018398
Fusion event
HTLV-1-chr22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
49217091/48821279 (Hg38)
End
49217091/48821279 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA22A
Nearest miRNA
hsa-let-7a-3/Upstream/40926; hsa-mir-12114/Downstream/722114;
Nearest TSS
ENST00000624155/Upstream/128032; ENST00000380981/Downstream/45491;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/69883, chr22-CpG: 18/Downstream/80682
Nearby gene
MIR4535(+40926) ;
Upstream sequence
tgGAAGCCACATCCCAGTGAGCGGTGGGCCAGGTGGGACCGGCAAGCCCAGTACCCCCCGCCCTTGGTCCCTAGGGTCTCTGTGGCTCCCTGGAAGACGC
Downstream sequence
AGCTTCTGCGAGAAGGGGATGCAGGGCTTGGCTATCTTCAGCCGCTCCAAAAGGCTGGCTTTGATGGTGCTTAGACCATGGTGGGTATTGAGCCGTAAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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