Basic Information
VIS ID
TVIS44018425
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
q27.3
Reference genome
GRCh37/hg19
Start
143127949/144044843 (Hg38)
End
143127949/144044843 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRAXA
Nearest miRNA
hsa-let-7f-2/Upstream/3118612; hsa-mir-105-1/Downstream/1947907;
Nearest TSS
ENST00000429181/Upstream/287106; ENST00000370493/Downstream/1188776;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/409717, chrX-CpG: 63/Downstream/1586060
Nearby gene
UBE2NL(+159592) ;
Upstream sequence
ACACAATAGGAGTCAGGTATGAGGAAACTCCTTCCCACTGAATCTACTCACAAAGAGAAAGTCCCCCAAAAGGAATGTTTTCCCCTTTTTTGTACACAAT
Downstream sequence
CACTAGATGTTAGTGTCCAACATGATCAACAGTCTGCACCGCTCCTTTCCTTAATCTTTCCAAAACAACGtccttctcaacgtgatgcaactcttcatta
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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