VISDB Viral Integration Site DataBase

VIS ID

TVIS44018430

Fusion event

HTLV-1-HCFC1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chrX

Cytoband

q28

Reference genome

Start

End

153218672/153953221 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRAXE ; FRAXF

Target gene

miRNAs that regulate target gene

hsa-mir-1296-5p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-149-5p ; hsa-mir-222-3p ; hsa-mir-183-5p ; hsa-mir-92a-3p ; hsa-mir-23a-3p ; hsa-let-7b-5p ; hsa-mir-1228-5p ; hsa-mir-654-5p ; hsa-mir-541-3p ; hsa-mir-6766-5p ; hsa-mir-6756-5p ; hsa-mir-6825-5p ; hsa-mir-7106-5p ; hsa-mir-885-3p ; hsa-mir-766-5p ; hsa-mir-4749-5p ; hsa-mir-6820-5p ; hsa-mir-4706 ; hsa-mir-6889-5p ; hsa-mir-6777-5p ; hsa-mir-4781-5p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-4662a-5p ; hsa-mir-4480 ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6752-3p ; hsa-mir-3616-5p ; hsa-mir-4311 ; hsa-mir-4433b-3p ; hsa-mir-4731-5p ; hsa-mir-4795-5p ; hsa-mir-548ac ; hsa-mir-548ae-3p ; hsa-mir-548ah-3p ; hsa-mir-548aj-3p ; hsa-mir-548am-3p ; hsa-mir-548aq-3p ; hsa-mir-548bb-3p ; hsa-mir-548d-3p ; hsa-mir-548h-3p ; hsa-mir-548j-3p ; hsa-mir-548x-3p ; hsa-mir-548z ; hsa-mir-5589-5p ; hsa-mir-5681a ; hsa-mir-573 ; hsa-mir-6731-5p ; hsa-mir-6739-5p ; hsa-mir-6804-5p ; hsa-mir-8085 ; hsa-mir-92b-5p

Nearest miRNA

hsa-let-7f-2/Upstream/617684; hsa-mir-1184-1/Downstream/27876;

Nearest TSS

Nearest CpG islands

None/Target, chrX-CpG: 62/Upstream/17750, chrX-CpG: 28/Downstream/146

Upstream sequence

GAGGAGAGGGGCCAGAGCCAGGCAGCAGGGCTGAGAAGCAAGCCAGCCCTCACCTTTCCTTGTGGGCCTAAGTTTTCATTCTTGATGGGCCAGCTCCAGC

Downstream sequence

CCATGTTAAATAGGGAGGGGACAGTGGTTCTCTGACCAGCATGAGGAGAAAGGCCCTTGAGACCCCCGGTCAGGTTTAACCCGTCCTCAGTCACCCTGGC