Basic Information
VIS ID
TVIS44018434
Fusion event
HTLV-1-LOC105373146 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.12
Reference genome
GRCh37/hg19
Start
21164724/21146606 (Hg38)
End
21164724/21146606 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105373146
Nearest miRNA
hsa-mir-23c/Upstream/1129419; hsa-let-7f-2/Downstream/7348949;
Nearest TSS
ENST00000429181/Upstream/15110; ENST00000645679/Downstream/226195;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/877913, chrX-CpG: 163/Downstream/227111
Nearby gene
CNKSR2(+227812) ;
Upstream sequence
ttttagtagagatggtgtttcaccatgttggccaagctggtctcgaactcctggcttcaagtgatcagcctacctcagcctcccaaagtgttgggaatac
Downstream sequence
aggcgtgagccactgcacccggccatgacaacctatttcaaccgaggaaggtgctacctgtgagctagttcttacttgtattccatagaactattctttc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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