Basic Information
VIS ID
TVIS44018437
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
30203661/30185544 (Hg38)
End
30203661/30185544 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRAXC
Nearest miRNA
hsa-mir-23c/Upstream/611186; hsa-let-7f-2/Downstream/2398112;
Nearest TSS
ENST00000429181/Upstream/268081; ENST00000378988/Downstream/30016;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/2321489, chrX-CpG: 30/Downstream/61511
Nearby gene
MAGEB2(+30014) ;
Upstream sequence
taaatgagaacttcacttccccattttcccacctgaatgttgccttttggcccaccatgctcccatcctgtgcccgtaaaaaccccaagctccactggca
Downstream sequence
gagcagcagactggtgtggcgtagcaggacagcacatggaagagagaagcagttgaacattgagaggaaaagaagcagctggatagtggaaactacggtc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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