Basic Information
VIS ID
TVIS44018438
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p21.2
Reference genome
GRCh37/hg19
Start
30545310/30527193 (Hg38)
End
30545310/30527193 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRAXC
Nearest miRNA
hsa-mir-23c/Upstream/952835; hsa-let-7f-2/Downstream/2056463;
Nearest TSS
ENST00000429181/Upstream/217595; ENST00000378941/Downstream/50651;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/217642, chrX-CpG: 88/Downstream/125429
Nearby gene
CXorf21(No orient, 31631)
Upstream sequence
aatcttcacaaatggcattttatatagttctgcaAtgccgagaccagctcggtcggtcgtggacaccctaacccagcggcgctagaggaattaaagacac
Downstream sequence
acacacagaaatatagagtgtggagtgggaaatcaggggactcacagccttcagagctgagagccccgaacagagtttgacccacctatttattgacagc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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