Basic Information
VIS ID
TVIS44018447
Fusion event
HTLV-1-FAM120C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
54123892/54097459 (Hg38)
End
54123892/54097459 (Hg38)
Orient
-
Location type
Intronic
Target gene
FAM120C
miRNAs that regulate target gene
hsa-mir-133a-3p ; hsa-mir-18a-5p
Nearest miRNA
hsa-let-7f-2/Upstream/540185; hsa-mir-105-1/Downstream/1354036;
Nearest TSS
ENST00000429181/Upstream/48501; ENST00000375151/Downstream/85319;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/52581, chrX-CpG: 79/Downstream/85047
Upstream sequence
gggcatgatggttcatgcctataatcccaacactttgtgaggcggaggccaggagTAGCAAGACCCTATCTCTACCAGAAAATAAAAAAAGAGAGGAAAA
Downstream sequence
GCGAGAGAGCTAGAATGGCTTCTGTTTCTTCTAAGCAAATGAGTCTGAAGAGACTGTCATTTACCCATCTGTGCTATCTTAGATAGCTATTCTGATATCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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