Basic Information
VIS ID
TVIS44018457
Fusion event
HTLV-1-chrX integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chrX
Cytoband
p22.31
Reference genome
GRCh37/hg19
Start
7273618/7355577 (Hg38)
End
7273618/7355577 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRAXB
Nearest miRNA
hsa-mir-3690-1/Upstream/207640; hsa-let-7f-2/Downstream/771388;
Nearest TSS
ENST00000429181/Upstream/136121; ENST00000341408/Downstream/486685;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/207130, chrX-CpG: 49/Downstream/571459
Nearby gene
STS(+936) ;
Upstream sequence
CAATGGGTGCAAAAATAAATACACAAAGTACCATATTTACAAAGATATGCATATTCTCCAGTGCGCAGGGCCCAATGGTTGCTACATTTGGAATAGAAAC
Downstream sequence
TATCTCATGGTTCAAATATACAGATTCATCTCAGTGAGTGCTGAGCAAGATGATATTTTCCTGTTTCCCTTATAGTAATGTTGGCACCATATGAGCCACT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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